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DermACELL

It eliminates more than 97% of the DNA.
It does not need to be refrigerated / frozen.
Allows storage at room temperature of 15 to 40 °C.
Biocompatible.

Differences between DermACELL and DermACELL AWM
DermACELL

  • Reconstruction of the breast after a mastectomy.

DermACELL AWM

  • Acute and chronic wounds.
  • Mainly diabetic foot ulcer (DFU), venous stasis ulcer (VSU).

The goal is an ECM (Extracellular Matrix) designed for …

  • Provide a biocompatible matrix.
  • Resembling an extracellular matrix (ECM) native to a human.
  • Support cell activity for rapid tissue regeneration.
  • Maintain inherent biomechanical properties.
  • Reduce the likelihood of infection.
  • Minimize preparation time.

MATRACELL decellularization technology.

Step One - Decellularization
To remove the donor cells from the allograft N-Lauroylsarcosinate (NLS) is used as an anionic, non-denaturing detergent.

To extract DNA from the donor, Benzonase®, a recombinant endonuclease, is used to efficiently degrade DNA without involving the risk associated with other endonucleases, such as prion diseases.

Step Two - Rinse

In a process in which USP grade normal saline is used, where the decellularization reactive residues and the donor cell remnants are removed from the allograft.

Step Three - Preservation

The processed allograft is preserved with LifeNet Health patented solution consisting of glycerol USP and USP saline. This allows the decellularized dermis to be stored at room temperature.

Step Four - Sterilization

This final step involves the use of a low dose of gamma radiation performed at ultra low temperatures. The final allograft has a Sterility Assurance Level (SAL) of 10-6.

More info in PDF

Technologies

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Av. Tepeyac #816

Col. Chapalita Oriente

Zapopan, Jalisco

México

contacto@bioimplants.mx

✆  (01 33) 20 01 06 44

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